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Cellular signal processing : an introduction to the molecular mechanisms of signal / Friedrich Marks, Ursula Klingmller, Karin Mller-Decker.

By: Marks, Friedrich, 1936-Contributor(s): Klingmller, Ursula | Mller-Decker, KarinPublisher: New York ; Abingdon : Garland Science, c2009Description: xiii, 634 p. : ill. ; 28 cm001: 41421ISBN: 0815342152 (pbk.) :; 9780815342151 (pbk.) :Subject(s): Cellular signal transduction | Signal Transduction -- physiology | Intracellular Signaling Peptides and Proteins -- physiologyDDC classification: 571.74 MAR LOC classification: QP517.C45 | M37 2009
Holdings
Item type Current library Collection Call number Copy number Status Date due Barcode
Book MAIN LIBRARY Book PRINT 571.74 MAR (Browse shelf(Opens below)) 1 Available 100458

Enhanced descriptions from Syndetics:

Cellular Signal Processing is intended for use in signal transduction courses for undergraduate and graduate students. It offers a unifying view of cell signaling that is based on the concept of protein interactions acting as sophisticated data processing networks that govern intracellular and extracellular communication. The content is guided by three major principles that are central to signal transduction: the protein network, its energy supply, and its evolution. It includes coverage of all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling. It also highlights the clinical aspects of cell signaling in health and disease.

Includes bibliographical references and index.

Table of contents provided by Syndetics

  • 1 The "Brain of the Cell": Data Processing by Protein Networks
  • 2 Supplying the Network with Energy: Basic Biochemistry of Signal Transduction
  • 3 Evolution of Cellular Data Processing
  • 4 Basic Equipment: G-Proteins, Second Messengers, and Protein Kinases
  • 5 Signal Transduction by Receptors with Seven Transmembrane Domains
  • 6 Signal Transduction by Serine/Threonine Kinase-Coupled Receptors
  • 7 Signal Transduction by Tyrosine Kinase- and Protein Phosphatase-Coupled Receptors: A Late Invention of Evolution
  • 8 Gene Transcription: The Ultimate Target of Signal Transduction
  • 9 Signals Controlling mRNA Translation
  • 10 Signal Transduction by Small G-proteins: The Art of Molecular Targeting
  • 11 Mitogen-activated Protein Kinase and Nuclear Factor ¿ß Modules
  • 12 Cancer and Regulation of Cell Division
  • 13 Signal Transduction by Proteolysis and Programmed Cell Death
  • 14 Signal Transduction by Ions
  • 15 Sensory Signal Processing
  • 16 Signaling at Synapses: Neurotransmitters and Their Receptors
  • 17 Putting Together the Pieces: The Approach of Systems Biology

Reviews provided by Syndetics

CHOICE Review

Marks, Klingmuller, and Muller-Decker (all, Univ. of Heidelberg, Germany) provide a refreshing approach to cell signaling through a holistic cell biology viewpoint. The authors provide detailed descriptions of tradition cell signaling pathways using classic cell examples. Marks and colleagues walk the reader through basic concepts, proceed to an information framework, and then provide detail and examples. This 17-chapter work is a useful reference for advanced readers (without the usual molecular cell background) seeking to understand cell signaling. It will complement collections for institutions that promote integrated learning across several disciplines in science, but may not be appropriate for libraries that already possess extensive holdings in cell signaling biology. Summing Up: Recommended. Upper-division undergraduates through professionals. L. Swatzell Southeast Missouri State University

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